/* =========================================================
   Saccade — site-v2.css
   Editorial / clinical / data-rich. No SaaS gradient slop.
   ========================================================= */

:root{
  --bg:#FAFAF7;
  --bg-warm:#F4F0E8;
  --ink:#141412;
  --ink-soft:#2A2A26;
  --muted:#6B6B65;
  --muted-2:#9C9A93;
  --rule:rgba(20,20,18,.10);
  --rule-strong:rgba(20,20,18,.18);
  --accent:#C13B2A;
  --accent-deep:#8A2818;
  --accent-tint:#F6E7E2;
  --hero-bg:#0C0B09;
  --hero-fg:#F2EBE0;
  --hero-muted:#7C7165;
  --hero-rule:rgba(242,235,224,.14);
  --hero-rule-strong:rgba(242,235,224,.22);
  --tint:#F2EDE4;
  --paper:#FFFDF8;
  --data-blue:#1F4F73;
}

*{box-sizing:border-box;}
html,body{margin:0;padding:0;}
html{scroll-behavior:smooth;}
body{
  background:var(--bg);
  color:var(--ink);
  font-family:"Instrument Sans", ui-sans-serif, system-ui, sans-serif;
  font-size:17px;
  line-height:1.55;
  -webkit-font-smoothing:antialiased;
  text-rendering:optimizeLegibility;
  overflow-x:hidden;
}
img{display:block;max-width:100%;}
a{color:inherit;text-decoration:none;}
::selection{background:var(--accent);color:#fff;}

.serif{font-family:"Source Serif 4", Georgia, serif;font-weight:600;letter-spacing:-0.014em;line-height:1.05;}
.mono{font-family:"IBM Plex Mono", ui-monospace, Menlo, monospace;font-variant-numeric:tabular-nums;}

/* ============ LAYOUT TOKENS ============ */
.wrap{max-width:900px;margin:0 auto;padding:0 40px;}
.wide{max-width:1240px;margin:0 auto;padding:0 40px;}
.xwide{max-width:1400px;margin:0 auto;padding:0 40px;}
section{padding:120px 0;position:relative;}
.eyebrow{
  font-family:"IBM Plex Mono", monospace;
  font-size:12px;letter-spacing:0.08em;
  color:var(--muted);
  display:flex;align-items:center;gap:12px;
  margin-bottom:56px;
  text-transform:uppercase;
}
.eyebrow::before{
  content:"";width:32px;height:1px;background:var(--accent);display:inline-block;
}
.eyebrow .num{color:var(--ink);font-weight:500;}
.eyebrow .dot{color:var(--rule-strong);margin:0 4px;}
h2.serif{font-size:clamp(32px,3.6vw,52px);margin:0 0 24px;text-wrap:balance;letter-spacing:-0.02em;}
h3.serif{font-size:clamp(22px,2.2vw,28px);margin:0 0 14px;letter-spacing:-0.012em;}
.lede{font-size:19px;line-height:1.55;color:var(--ink-soft);max-width:62ch;margin:0 0 56px;text-wrap:pretty;}
.lede strong{color:var(--ink);font-weight:600;}

/* ============ NAV ============ */
.nav{
  position:fixed;top:0;left:0;right:0;z-index:50;
  background:rgba(250,250,247,.78);
  backdrop-filter:saturate(1.2) blur(14px);
  -webkit-backdrop-filter:saturate(1.2) blur(14px);
  transition:border-color .25s, background .25s;
  border-bottom:1px solid transparent;
}
.nav.scrolled{border-bottom-color:var(--rule);}
.nav-inner{
  max-width:1400px;margin:0 auto;
  padding:16px 40px;
  display:grid;grid-template-columns:1fr auto 1fr;align-items:center;gap:24px;
}
.wordmark{justify-self:start;display:flex;align-items:center;gap:10px;}
.wordmark-img{height:26px;width:auto;display:block;}
.nav.scrolled .wordmark-img{filter:invert(1);}
.nav-links{display:flex;gap:32px;align-items:center;justify-self:center;}
.nav-links a{
  font-family:"IBM Plex Mono", monospace;
  font-size:11px;letter-spacing:0.16em;text-transform:uppercase;
  color:var(--ink);opacity:.7;transition:opacity .15s;
}
.nav-links a:hover{opacity:1;}
.nav-links a.active{opacity:1;}
.nav-links a.active::after{
  content:"";display:block;height:1px;background:var(--accent);margin-top:4px;
}
.nav-actions{justify-self:end;display:flex;align-items:center;gap:12px;}
.nav-cta{
  font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:0.14em;text-transform:uppercase;
  border:1px solid var(--ink);color:var(--ink);
  padding:9px 14px;
  display:inline-flex;align-items:center;gap:8px;white-space:nowrap;
  transition:background .15s, color .15s;
}
.nav-cta:hover{background:var(--ink);color:var(--bg);}
.nav.over-dark{background:transparent;border-bottom:none;}
.nav.over-dark .nav-links a{color:rgba(242,235,224,.65);}
.nav.over-dark .nav-links a:hover{color:#F2EBE0;}
.nav.over-dark .nav-links a.active{color:#F2EBE0;}
.nav.over-dark .nav-cta{border-color:rgba(242,235,224,.28);color:#F2EBE0;}
.nav.over-dark .nav-cta:hover{background:var(--accent);border-color:var(--accent);color:#fff;}

/* ============ HERO ============ */
.hero{
  position:relative;
  background:var(--hero-bg);
  color:var(--hero-fg);
  min-height:100vh;
  padding:120px 0 56px;
  margin-top:0;
  overflow:hidden;
  display:flex;
  flex-direction:column;
  justify-content:center;
}
/* dotted backdrop */
.hero::before{
  content:"";
  position:absolute;inset:0;
  background-image:radial-gradient(rgba(242,235,224,.10) 1px, transparent 1.4px);
  background-size:22px 22px;
  mask-image:radial-gradient(ellipse 70% 60% at 50% 55%, transparent 30%, black 95%);
  -webkit-mask-image:radial-gradient(ellipse 70% 60% at 50% 55%, transparent 30%, black 95%);
  pointer-events:none;
}
/* live saccade canvas behind */
.hero .saccade-canvas{
  position:absolute;inset:0;width:100%;height:100%;
  z-index:1;opacity:.55;pointer-events:none;
}
.hero-inner{
  position:relative;z-index:3;
  width:100%;
  max-width:1240px;margin:0 auto;padding:0 40px;
  display:flex;flex-direction:column;align-items:flex-start;text-align:left;
  gap:32px;
}
.hero-status{
  font-family:"IBM Plex Mono",monospace;
  font-size:11px;letter-spacing:0.08em;color:var(--hero-muted);
  display:inline-flex;align-items:center;gap:14px;flex-wrap:wrap;
  border:1px solid var(--hero-rule);
  padding:8px 14px;
  background:rgba(12,11,9,.6);
  backdrop-filter:blur(4px);
  max-width:100%;
}
.hero-status .pulse{
  width:6px;height:6px;border-radius:50%;background:var(--accent);
  box-shadow:0 0 0 4px rgba(193,59,42,.18);
  animation:hpulse 2s ease-in-out infinite;
}
@keyframes hpulse{0%,100%{box-shadow:0 0 0 4px rgba(193,59,42,.18);}50%{box-shadow:0 0 0 8px rgba(193,59,42,.06);}}
.hero-status strong{color:var(--hero-fg);font-weight:500;}
.hero-status .sep{color:rgba(242,235,224,.22);}

.hero h1{
  font-family:"Source Serif 4",serif;font-weight:600;
  font-size:clamp(40px,5.4vw,88px);
  line-height:1.02;letter-spacing:-0.028em;
  margin:0;max-width:18ch;
  text-wrap:balance;
  color:var(--hero-fg);
}
.hero h1 .acc{color:var(--accent);font-style:italic;font-weight:500;}
.hero h1 .alt{color:var(--hero-muted);font-style:italic;font-weight:500;}
.hero h1 .blink-cursor{
  display:inline-block;width:.5em;height:.78em;
  background:var(--accent);margin-left:.08em;vertical-align:-0.04em;
  animation:blink 1.05s steps(1) infinite;
}
@keyframes blink{50%{opacity:0;}}

.hero-sub{
  max-width:48ch;color:rgba(242,235,224,.78);font-size:18px;line-height:1.55;
  margin:0;text-wrap:pretty;
}
.hero-sub strong{color:var(--hero-fg);font-weight:500;}

.hero-ctas{display:flex;gap:10px;align-items:stretch;flex-wrap:wrap;margin-top:8px;}
.hero-ctas .primary{
  background:var(--accent);color:#fff;
  font-family:"IBM Plex Mono",monospace;font-size:13px;letter-spacing:0.02em;
  padding:16px 22px;display:inline-flex;align-items:center;gap:10px;
  border:1px solid var(--accent);
  transition:background .15s, color .15s, border-color .15s, transform .15s;
}
.hero-ctas .primary:hover{background:#0E0D0B;color:var(--accent);transform:translateY(-1px);}
.hero-ctas .secondary{
  background:transparent;color:var(--hero-fg);
  border:1px solid var(--hero-rule-strong);
  font-family:"IBM Plex Mono",monospace;font-size:13px;letter-spacing:0.02em;
  padding:16px 18px;display:inline-flex;align-items:center;gap:10px;
  transition:border-color .15s, color .15s;
}
.hero-ctas .secondary:hover{border-color:var(--hero-fg);}

.hero-bottom{
  position:relative;z-index:3;
  width:100%;max-width:1240px;margin:80px auto 0;padding:0 40px;
  display:grid;grid-template-columns:repeat(4,1fr);
  border-top:1px solid var(--hero-rule);
}
.hero-bottom .cell{
  padding:24px 24px 0 0;border-right:1px solid var(--hero-rule);
  display:flex;flex-direction:column;gap:6px;
}
.hero-bottom .cell:not(:first-child){padding-left:24px;}
.hero-bottom .cell:last-child{border-right:none;}
.hero-bottom .cell .k{
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;
  color:var(--hero-muted);
}
.hero-bottom .cell .v{
  font-family:"Source Serif 4",serif;font-weight:600;font-size:24px;color:var(--hero-fg);
  letter-spacing:-0.015em;line-height:1.1;
}
.hero-bottom .cell .v .accent{color:var(--accent);font-style:italic;font-weight:500;}
.hero-bottom .cell .vs{font-family:"IBM Plex Mono",monospace;font-size:11px;color:var(--hero-muted);letter-spacing:0.04em;margin-top:2px;}

/* tiny corner annotation */
.hero-corner{
  position:absolute;right:40px;bottom:40px;z-index:3;
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.12em;
  color:var(--hero-muted);text-transform:uppercase;
  display:flex;flex-direction:column;align-items:flex-end;gap:6px;
}
.hero-corner span{display:flex;align-items:center;gap:8px;}
.hero-corner .dot{width:5px;height:5px;background:var(--accent);border-radius:50%;}

/* ============ TRUST STRIP ============ */
.trust{
  background:var(--ink);
  color:var(--hero-fg);
  padding:28px 0;
  border-bottom:1px solid rgba(242,235,224,.08);
}
.trust-inner{
  max-width:1400px;margin:0 auto;padding:0 40px;
  display:flex;align-items:center;justify-content:space-between;gap:32px;
  flex-wrap:wrap;
}
.trust .lbl{
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.18em;text-transform:uppercase;
  color:var(--hero-muted);white-space:nowrap;
}
.trust .marks{
  display:flex;align-items:center;gap:36px;flex-wrap:wrap;flex:1;justify-content:center;
}
.trust .mark{
  font-family:"Source Serif 4",serif;font-weight:600;font-size:15px;color:rgba(242,235,224,.78);
  letter-spacing:-0.005em;
  display:inline-flex;align-items:center;gap:8px;
  transition:color .15s;
}
.trust .mark:hover{color:var(--hero-fg);}
.trust .mark .m-dot{width:5px;height:5px;background:var(--accent);border-radius:50%;}
.trust .mark .m-mono{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:0.12em;text-transform:uppercase;color:var(--hero-muted);}

/* ============ MISSION ============ */
.mission{padding:140px 0;background:var(--bg);}
.mission .wrap{max-width:980px;}
.mission h2{
  font-family:"Source Serif 4",serif;font-weight:500;
  font-size:clamp(30px,4vw,52px);line-height:1.15;letter-spacing:-0.018em;
  margin:0;color:var(--ink);max-width:30ch;
}
.mission h2 .acc{color:var(--accent);font-style:italic;}
.mission h2 .strike{text-decoration:line-through;color:var(--muted);font-weight:400;}
.mission .pf{
  margin-top:48px;display:grid;grid-template-columns:repeat(3,1fr);gap:0;
  border-top:1px solid var(--ink);
}
.mission .pf .cell{padding:24px 24px 0 0;border-right:1px solid var(--rule);}
.mission .pf .cell:not(:first-child){padding-left:24px;}
.mission .pf .cell:last-child{border-right:none;}
.mission .pf .pk{font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;color:var(--muted);margin-bottom:8px;}
.mission .pf .pv{font-family:"Source Serif 4",serif;font-size:30px;font-weight:600;line-height:1.1;letter-spacing:-0.015em;color:var(--ink);}
.mission .pf .pv .acc{color:var(--accent);}
.mission .pf .ps{font-size:13px;color:var(--muted);margin-top:6px;line-height:1.45;max-width:24ch;}

/* ============ STAKES — biomarker chart ============ */
.stakes{background:var(--bg);padding:140px 0;border-top:1px solid var(--rule);}
.stakes-grid{
  display:grid;grid-template-columns:0.85fr 1.15fr;gap:80px;align-items:center;
}
.stakes h2{max-width:18ch;}
.stakes p{font-size:17px;line-height:1.6;color:var(--ink-soft);margin:0 0 16px;max-width:50ch;}
.stakes p strong{color:var(--ink);font-weight:600;}
.stakes-chart{
  position:relative;background:var(--paper);
  border:1px solid var(--rule);
  padding:32px 28px 24px;
  aspect-ratio:5/4;
}
.stakes-chart svg{width:100%;height:100%;display:block;}
.stakes-chart .ch-label{
  position:absolute;top:24px;left:28px;
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;color:var(--muted);
}
.stakes-chart .ch-title{
  position:absolute;top:24px;right:28px;
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;color:var(--muted);
}
.stakes-chart .legend{
  position:absolute;left:28px;bottom:14px;display:flex;gap:20px;
  font-family:"IBM Plex Mono",monospace;font-size:10.5px;letter-spacing:0.04em;color:var(--ink);
}
.stakes-chart .legend .sw{width:14px;height:2px;display:inline-block;margin-right:6px;vertical-align:middle;}

/* ============ HOW (TASKS) ============ */
.how{padding:140px 0;background:var(--bg-warm);border-top:1px solid var(--rule);}
.how h2{max-width:22ch;}
.how .sub{font-size:17px;color:var(--ink-soft);max-width:54ch;margin:0 0 56px;line-height:1.55;}
.tasks{
  display:grid;grid-template-columns:repeat(4,1fr);gap:0;
  border-top:1px solid var(--ink);border-bottom:1px solid var(--ink);
}
.task{
  padding:28px 24px;position:relative;
  display:flex;flex-direction:column;gap:12px;
  border-right:1px solid var(--rule);background:var(--paper);
}
.task:last-child{border-right:none;}
.task .n{font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;color:var(--accent);text-transform:uppercase;}
.task .t{font-family:"Source Serif 4",serif;font-weight:600;font-size:19px;letter-spacing:-0.008em;line-height:1.15;}
.task .d{font-size:13.5px;color:var(--muted);line-height:1.5;}
.task .viz{
  width:100%;aspect-ratio:1.4;background:#0E0D0B;position:relative;overflow:hidden;
  border:1px solid var(--rule);
  margin-top:4px;
}
.task .viz canvas{position:absolute;inset:0;width:100%;height:100%;}
.task .viz .lbl{
  position:absolute;bottom:8px;left:10px;
  font-family:"IBM Plex Mono",monospace;font-size:9px;letter-spacing:0.14em;color:rgba(242,235,224,.6);text-transform:uppercase;
}
.task .viz .hz{position:absolute;top:8px;right:10px;font-family:"IBM Plex Mono",monospace;font-size:9px;letter-spacing:0.06em;color:rgba(242,235,224,.5);}

/* 4-step process bar */
.process{margin-top:64px;display:grid;grid-template-columns:repeat(4,1fr);gap:0;border-top:1px solid var(--ink);}
.process .step{padding:24px 24px 24px 0;border-right:1px solid var(--rule);position:relative;}
.process .step:not(:first-child){padding-left:24px;}
.process .step:last-child{border-right:none;}
.process .step .pn{font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;color:var(--muted);}
.process .step .pt{font-family:"Source Serif 4",serif;font-weight:600;font-size:18px;margin-top:6px;letter-spacing:-0.008em;}
.process .step .pd{font-size:13px;color:var(--muted);margin-top:6px;line-height:1.5;}
.process .step .pr-arr{
  position:absolute;top:30px;right:-6px;width:12px;height:1px;background:var(--ink);
}
.process .step:last-child .pr-arr{display:none;}
.process .step .pr-arr::after{
  content:"";position:absolute;right:0;top:-3px;
  border-top:3px solid transparent;border-bottom:3px solid transparent;border-left:5px solid var(--ink);
}

/* eye-IR figure */
.eye-figure{margin-top:64px;display:grid;grid-template-columns:1.05fr .95fr;gap:48px;align-items:center;}
.eye-figure .eye-frame{position:relative;background:#0e0e0d;aspect-ratio:5/4;overflow:hidden;border:1px solid var(--rule);}
.eye-figure .eye-frame img{width:100%;height:100%;object-fit:cover;filter:contrast(1.06) brightness(.95);}
.eye-figure .eye-frame .ovl{
  position:absolute;inset:0;display:flex;align-items:flex-end;justify-content:space-between;
  padding:18px;color:rgba(255,255,255,.78);
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;
}
.eye-figure .eye-frame .target{
  position:absolute;left:50%;top:48%;width:130px;height:130px;
  border:1px solid rgba(193,59,42,.5);border-radius:50%;
  transform:translate(-50%,-50%);
}
.eye-figure .eye-frame .target::after{
  content:"";position:absolute;left:50%;top:50%;width:6px;height:6px;
  background:var(--accent);border-radius:50%;transform:translate(-50%,-50%);
  box-shadow:0 0 0 2px rgba(193,59,42,.3);
}
.eye-figure .eye-frame .corner{
  position:absolute;width:14px;height:14px;border-color:rgba(255,255,255,.4);
}
.eye-figure .eye-frame .corner.tl{top:14px;left:14px;border-top:1px solid;border-left:1px solid;}
.eye-figure .eye-frame .corner.tr{top:14px;right:14px;border-top:1px solid;border-right:1px solid;}
.eye-figure .eye-frame .corner.bl{bottom:14px;left:14px;border-bottom:1px solid;border-left:1px solid;}
.eye-figure .eye-frame .corner.br{bottom:14px;right:14px;border-bottom:1px solid;border-right:1px solid;}
.eye-figure p{font-size:16.5px;line-height:1.6;margin:0;color:var(--ink-soft);}
.eye-figure p strong{color:var(--ink);font-weight:600;}

/* ============ BENTO — Why us ============ */
.moat{padding:140px 0;background:var(--bg);border-top:1px solid var(--rule);}
.moat h2{max-width:18ch;}
.moat .sub{font-size:17px;color:var(--ink-soft);max-width:50ch;margin:0 0 56px;line-height:1.55;}
.bento{
  display:grid;
  grid-template-columns:repeat(6,1fr);
  grid-auto-rows:180px;
  gap:14px;
}
.bento .cell{
  background:var(--paper);
  border:1px solid var(--rule);
  padding:22px 22px;
  display:flex;flex-direction:column;justify-content:space-between;
  position:relative;overflow:hidden;
  transition:transform .25s ease, border-color .25s;
}
.bento .cell:hover{transform:translateY(-2px);border-color:var(--rule-strong);}
.bento .cell .ix{
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;color:var(--accent);text-transform:uppercase;
}
.bento .cell h3{
  font-family:"Source Serif 4",serif;font-weight:600;font-size:22px;letter-spacing:-0.012em;line-height:1.15;margin:8px 0 8px;color:var(--ink);text-wrap:balance;
}
.bento .cell p{font-size:14px;line-height:1.5;color:var(--muted);margin:0;max-width:38ch;}
.bento .cell .tag{
  position:absolute;bottom:14px;right:18px;
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.12em;color:var(--muted);text-transform:uppercase;
}
.bento .c-1{grid-column:span 3;grid-row:span 2;background:var(--ink);color:var(--hero-fg);}
.bento .c-1 h3{color:var(--hero-fg);font-size:30px;max-width:14ch;}
.bento .c-1 p{color:rgba(242,235,224,.7);max-width:42ch;font-size:15px;}
.bento .c-1 .ix{color:var(--accent);}
.bento .c-1 .tag{color:rgba(242,235,224,.4);}
.bento .c-1 .headset{
  position:absolute;right:-40px;bottom:-30px;width:380px;opacity:.85;
  filter:drop-shadow(0 30px 60px rgba(0,0,0,.4));
  transform:rotate(-6deg);
}
.bento .c-2{grid-column:span 3;grid-row:span 1;}
.bento .c-3{grid-column:span 2;grid-row:span 1;}
.bento .c-4{grid-column:span 2;grid-row:span 1;background:var(--accent);color:#fff;}
.bento .c-4 h3{color:#fff;font-size:34px;max-width:8ch;}
.bento .c-4 p{color:rgba(255,255,255,.85);}
.bento .c-4 .ix{color:rgba(255,255,255,.6);}
.bento .c-4 .tag{color:rgba(255,255,255,.6);}
.bento .c-5{grid-column:span 3;grid-row:span 2;background:var(--bg-warm);}
.bento .c-5 .map-viz{position:absolute;left:0;right:0;top:60px;bottom:14px;}
.bento .c-6{grid-column:span 3;grid-row:span 1;}
.bento .c-7{grid-column:span 3;grid-row:span 1;}

/* small inline svg viz inside bento */
.bento .v-time{
  position:absolute;right:-10px;bottom:-10px;
  font-family:"Source Serif 4",serif;font-weight:600;font-size:140px;
  color:var(--accent-tint);line-height:1;letter-spacing:-0.04em;
  pointer-events:none;
}

/* ============ PHARMA ECONOMICS ============ */
.pharma{padding:140px 0;background:var(--ink);color:var(--hero-fg);border-top:1px solid var(--ink);}
.pharma .eyebrow{color:var(--hero-muted);}
.pharma .eyebrow .num{color:var(--hero-fg);}
.pharma .eyebrow::before{background:var(--accent);}
.pharma h2{color:var(--hero-fg);max-width:22ch;}
.pharma h2 .acc{color:var(--accent);font-style:italic;font-weight:500;}
.pharma .sub{color:rgba(242,235,224,.7);font-size:17px;max-width:54ch;margin:0 0 56px;line-height:1.55;}

.funnel{
  display:grid;grid-template-columns:1fr 1fr;gap:0;
  border:1px solid var(--hero-rule);
  background:rgba(242,235,224,.02);
}
.funnel .col{padding:36px 36px 32px;}
.funnel .col + .col{border-left:1px solid var(--hero-rule);}
.funnel .col .hd{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:0.18em;text-transform:uppercase;color:var(--hero-muted);margin-bottom:24px;}
.funnel .col.r .hd{color:var(--accent);}
.funnel .col .title{font-family:"Source Serif 4",serif;font-weight:600;font-size:22px;color:var(--hero-fg);margin-bottom:22px;letter-spacing:-0.012em;}
.funnel-stage{
  display:grid;grid-template-columns:1fr auto;align-items:baseline;gap:16px;
  padding:14px 0;border-top:1px solid var(--hero-rule);
}
.funnel-stage:first-of-type{border-top:none;}
.funnel-stage .stage-lbl{font-size:14.5px;color:rgba(242,235,224,.84);}
.funnel-stage .stage-num{font-family:"IBM Plex Mono",monospace;font-size:18px;color:var(--hero-fg);font-weight:500;letter-spacing:-0.01em;}
.funnel-stage .bar{
  grid-column:1 / -1;height:6px;background:rgba(242,235,224,.08);position:relative;margin-top:8px;overflow:hidden;
}
.funnel-stage .bar .fill{
  position:absolute;left:0;top:0;bottom:0;background:rgba(242,235,224,.4);transition:width 1.2s cubic-bezier(.2,.7,.2,1);
}
.funnel .col.r .bar .fill{background:var(--accent);}
.funnel-foot{
  padding:24px 36px;border-top:1px solid var(--hero-rule);
  display:grid;grid-template-columns:1fr 1fr;gap:0;
}
.funnel-foot .ff{padding-right:24px;}
.funnel-foot .ff + .ff{padding-left:36px;border-left:1px solid var(--hero-rule);}
.funnel-foot .ff .fk{font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;color:var(--hero-muted);margin-bottom:6px;}
.funnel-foot .ff .fv{font-family:"Source Serif 4",serif;font-weight:600;font-size:30px;color:var(--hero-fg);line-height:1.1;letter-spacing:-0.015em;}
.funnel-foot .ff.r .fv{color:var(--accent);font-style:italic;font-weight:500;}
.funnel-foot .ff .fs{font-family:"IBM Plex Mono",monospace;font-size:11px;color:var(--hero-muted);margin-top:4px;letter-spacing:0.04em;}

.pharma-foot{
  margin-top:48px;padding-top:32px;border-top:1px solid var(--hero-rule);
  font-size:17px;line-height:1.65;max-width:72ch;color:rgba(242,235,224,.82);
}
.pharma-foot strong{color:var(--hero-fg);font-weight:600;}

/* ============ AUDIENCE ============ */
.who{padding:140px 0;background:var(--bg);border-top:1px solid var(--ink);}
.who h2{max-width:22ch;}
.who .sub{font-size:17px;color:var(--ink-soft);max-width:54ch;margin:0 0 56px;line-height:1.55;}
.who-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:0;border-top:1px solid var(--ink);border-bottom:1px solid var(--ink);}
.who-grid .card{
  padding:32px 26px 28px;border-right:1px solid var(--rule);position:relative;
  display:flex;flex-direction:column;gap:14px;background:var(--paper);
  min-height:340px;
  transition:background .2s;
}
.who-grid .card:hover{background:var(--bg-warm);}
.who-grid .card:last-child{border-right:none;}
.who-grid .card .tag{font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;color:var(--accent);}
.who-grid .card .title{font-family:"Source Serif 4",serif;font-weight:600;font-size:22px;letter-spacing:-0.012em;line-height:1.15;color:var(--ink);}
.who-grid .card p{font-size:14.5px;line-height:1.55;color:var(--muted);margin:0;}
.who-grid .card p strong{color:var(--ink);font-weight:600;}
.who-grid .card .cta{
  margin-top:auto;
  font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:0.14em;text-transform:uppercase;
  color:var(--ink);display:inline-flex;align-items:center;gap:8px;padding-top:14px;border-top:1px solid var(--rule);
}
.who-grid .card .cta .ar{transition:transform .15s;}
.who-grid .card:hover .cta .ar{transform:translateX(3px);}

/* ============ SCIENCE ============ */
.science{padding:140px 0;background:var(--bg-warm);border-top:1px solid var(--rule);}
.science h2{max-width:22ch;}
.science .head{display:grid;grid-template-columns:1.2fr 0.8fr;gap:64px;align-items:end;margin-bottom:56px;}
.science .sub{font-size:17px;color:var(--ink-soft);max-width:54ch;margin:0;line-height:1.55;}
.science .stat-bar{
  display:flex;flex-direction:column;gap:8px;
  border-left:1px solid var(--ink);padding-left:24px;
}
.science .stat-bar .sk{font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;color:var(--muted);}
.science .stat-bar .sv{font-family:"Source Serif 4",serif;font-weight:600;font-size:48px;color:var(--accent);line-height:1;letter-spacing:-0.02em;}
.science .stat-bar .ss{font-size:13.5px;color:var(--muted);max-width:30ch;line-height:1.4;}

.papers{border-top:1px solid var(--ink);}
.paper{
  display:grid;grid-template-columns:240px 1fr 140px;gap:32px;
  padding:22px 0;border-bottom:1px solid var(--rule);
  align-items:baseline;transition:padding .2s, background .2s;
}
.paper:hover{padding-left:8px;}
.paper .src{font-family:"Source Serif 4",serif;font-weight:600;font-size:15.5px;color:var(--ink);letter-spacing:-0.005em;}
.paper .src .yr{font-family:"IBM Plex Mono",monospace;font-size:11px;color:var(--muted);font-weight:400;margin-left:8px;letter-spacing:0.06em;}
.paper .desc{font-size:15px;line-height:1.5;color:var(--ink-soft);max-width:62ch;}
.paper .stat{font-family:"IBM Plex Mono",monospace;font-size:12px;color:var(--accent);text-align:right;letter-spacing:0.02em;}

/* ============ EVIDENCE — IRB studies + clinical report ============ */
.evidence{padding:140px 0;background:var(--bg);border-top:1px solid var(--rule);}
.evidence h2{max-width:22ch;}
.evidence .sub{font-size:17px;color:var(--ink-soft);max-width:54ch;margin:0 0 56px;line-height:1.55;}
.evidence-grid{display:grid;grid-template-columns:1.1fr 0.9fr;gap:56px;align-items:start;}
.evidence-studies{display:flex;flex-direction:column;gap:0;border-top:1px solid var(--ink);}
.evidence-study{
  display:grid;grid-template-columns:120px 1fr;gap:24px;
  padding:24px 0;border-bottom:1px solid var(--rule);
  align-items:start;
}
.evidence-study .es-site{
  font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:0.12em;text-transform:uppercase;
  color:var(--accent);font-weight:500;
}
.evidence-study .es-title{font-family:"Source Serif 4",serif;font-weight:600;font-size:18px;line-height:1.25;letter-spacing:-0.008em;color:var(--ink);margin-bottom:6px;}
.evidence-study .es-desc{font-size:14.5px;color:var(--muted);line-height:1.55;}
.evidence-study .es-desc strong{color:var(--ink-soft);font-weight:500;}
.evidence-study .es-pi{font-family:"IBM Plex Mono",monospace;font-size:11px;color:var(--muted);letter-spacing:0.04em;margin-top:8px;}

.report-card{
  background:#0E0D0B;padding:6px;border:1px solid var(--ink);position:sticky;top:90px;
}
.report-card img{width:100%;display:block;}
.report-cap{
  margin-top:14px;display:flex;justify-content:space-between;align-items:baseline;
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.14em;text-transform:uppercase;color:var(--muted);
}

.badges{display:flex;gap:8px;margin-top:32px;flex-wrap:wrap;}
.badge{
  font-family:"IBM Plex Mono",monospace;font-size:10.5px;letter-spacing:0.12em;text-transform:uppercase;
  border:1px solid var(--rule-strong);padding:7px 11px;color:var(--ink);background:var(--paper);
}
.badge .d{color:var(--accent);margin-right:7px;}

/* ============ REGULATORY ============ */
.reg{padding:140px 0;background:var(--bg-warm);border-top:1px solid var(--rule);}
.reg h2{max-width:22ch;}
.reg-grid{display:grid;grid-template-columns:0.4fr 0.6fr;gap:80px;}
.reg .sub{font-size:17px;color:var(--ink-soft);max-width:46ch;margin:0;line-height:1.55;}
.reg-table{border-top:1px solid var(--ink);}
.reg-row{
  display:grid;grid-template-columns:140px 1fr;gap:32px;
  padding:24px 0;border-bottom:1px solid var(--rule);
  align-items:baseline;position:relative;
}
.reg-row::before{
  content:"";position:absolute;left:62px;top:32px;width:8px;height:8px;
  background:var(--bg-warm);border:1px solid var(--accent);border-radius:50%;
}
.reg-row .when{font-family:"IBM Plex Mono",monospace;font-size:12px;letter-spacing:0.04em;color:var(--accent);font-weight:500;}
.reg-row .what{font-size:15.5px;line-height:1.55;color:var(--ink);max-width:62ch;}
.reg-row .what em{font-style:normal;color:var(--muted);font-size:13px;display:block;margin-top:6px;font-family:"IBM Plex Mono",monospace;letter-spacing:0;}

/* ============ TEAM ============ */
.team{padding:140px 0;background:var(--bg);border-top:1px solid var(--rule);}
.team h2{max-width:24ch;}
.team .sub{font-size:17px;color:var(--ink-soft);max-width:54ch;margin:0 0 56px;line-height:1.55;}
.bench{display:grid;grid-template-columns:repeat(3,1fr);gap:48px 40px;}
.bench .b{display:flex;flex-direction:column;gap:12px;}
.bench .b .ph{width:100%;aspect-ratio:1;overflow:hidden;background:var(--tint);filter:saturate(.88);}
.bench .b .ph img{width:100%;height:100%;object-fit:cover;}
.bench .b .nm{font-family:"Source Serif 4",serif;font-weight:600;font-size:17px;letter-spacing:-0.005em;line-height:1.2;}
.bench .b .rl{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:0.04em;color:var(--muted);line-height:1.45;}

/* ============ CONTACT ============ */
.contact{padding:160px 0 120px;background:var(--ink);color:var(--hero-fg);}
.contact .eyebrow{color:var(--hero-muted);}
.contact .eyebrow .num{color:var(--hero-fg);}
.contact .eyebrow::before{background:var(--accent);}
.contact h2{
  font-family:"Source Serif 4",serif;font-weight:500;
  font-size:clamp(48px,7vw,108px);
  line-height:0.96;letter-spacing:-0.03em;
  margin:0 0 48px;color:var(--hero-fg);max-width:14ch;
}
.contact h2 .acc{color:var(--accent);font-style:italic;}
.contact-grid{display:grid;grid-template-columns:1fr 1fr;gap:48px;align-items:end;}
.contact-grid .lines{font-size:18px;line-height:1.9;}
.contact-grid .lines a{color:var(--accent);border-bottom:1px solid currentColor;}
.contact-grid .meta{font-family:"IBM Plex Mono",monospace;font-size:11px;letter-spacing:0.08em;color:var(--hero-muted);text-transform:uppercase;}
.contact-grid .meta div + div{margin-top:8px;}
.contact-ctas{display:flex;gap:10px;margin-top:32px;flex-wrap:wrap;}
.contact-ctas .c-btn{
  font-family:"IBM Plex Mono",monospace;font-size:13px;letter-spacing:0.02em;
  padding:16px 22px;display:inline-flex;align-items:center;gap:10px;
  border:1px solid var(--hero-rule-strong);color:var(--hero-fg);
  transition:border-color .15s, background .15s, color .15s;
}
.contact-ctas .c-btn.primary{background:var(--accent);border-color:var(--accent);color:#fff;}
.contact-ctas .c-btn.primary:hover{background:#fff;color:var(--accent);}
.contact-ctas .c-btn:hover{border-color:var(--hero-fg);}

/* ============ FOOTER ============ */
footer{
  border-top:1px solid rgba(242,235,224,.08);background:var(--ink);color:var(--hero-muted);padding:32px 0 40px;
}
footer .wide{
  display:flex;justify-content:space-between;align-items:flex-start;gap:32px;flex-wrap:wrap;
  font-family:"IBM Plex Mono",monospace;font-size:10px;letter-spacing:0.12em;text-transform:uppercase;
}
footer .legal{max-width:60ch;color:rgba(242,235,224,.45);text-transform:none;letter-spacing:0;font-size:11px;line-height:1.55;font-family:"Instrument Sans",sans-serif;}

/* ============ REVEAL ============ */
.reveal{opacity:0;transform:translateY(14px);transition:opacity .8s ease, transform .8s ease;}
.reveal.in{opacity:1;transform:none;}

/* ============ RESPONSIVE ============ */
@media (max-width:1080px){
  .bento{grid-template-columns:repeat(4,1fr);grid-auto-rows:170px;}
  .bento .c-1{grid-column:span 4;grid-row:span 2;}
  .bento .c-2{grid-column:span 2;}
  .bento .c-3{grid-column:span 2;}
  .bento .c-4{grid-column:span 2;}
  .bento .c-5{grid-column:span 2;grid-row:span 2;}
  .bento .c-6{grid-column:span 4;}
  .bento .c-7{grid-column:span 4;}
}
@media (max-width:920px){
  section{padding:96px 0;}
  .wrap,.wide,.xwide{padding:0 24px;}
  .nav-inner{padding:14px 24px;}
  .nav-links{display:none;}
  .hero-inner{padding:0 24px;}
  .hero h1{font-size:clamp(36px,8vw,54px);}
  .hero-bottom{grid-template-columns:repeat(2,1fr);padding:0 24px;}
  .hero-bottom .cell:nth-child(2){border-right:none;}
  .hero-bottom .cell:nth-child(3),.hero-bottom .cell:nth-child(4){border-top:1px solid var(--hero-rule);padding-top:24px;margin-top:0;}
  .hero-corner{display:none;}
  .mission .pf{grid-template-columns:1fr;}
  .mission .pf .cell{border-right:none;border-bottom:1px solid var(--rule);padding:20px 0;}
  .stakes-grid{grid-template-columns:1fr;gap:48px;}
  .tasks{grid-template-columns:1fr 1fr;}
  .task:nth-child(2){border-right:none;}
  .task:nth-child(1),.task:nth-child(2){border-bottom:1px solid var(--rule);}
  .process{grid-template-columns:1fr 1fr;}
  .process .step:nth-child(2){border-right:none;}
  .process .step:nth-child(1),.process .step:nth-child(2){border-bottom:1px solid var(--rule);padding-bottom:24px;}
  .process .step .pr-arr{display:none;}
  .eye-figure{grid-template-columns:1fr;gap:32px;}
  .bento{grid-template-columns:1fr;grid-auto-rows:auto;}
  .bento .cell{min-height:180px;}
  .funnel{grid-template-columns:1fr;}
  .funnel .col + .col{border-left:none;border-top:1px solid var(--hero-rule);}
  .funnel-foot{grid-template-columns:1fr;}
  .funnel-foot .ff + .ff{border-left:none;border-top:1px solid var(--hero-rule);padding-left:0;padding-top:20px;margin-top:20px;}
  .who-grid{grid-template-columns:1fr 1fr;}
  .who-grid .card:nth-child(2){border-right:none;}
  .who-grid .card:nth-child(1),.who-grid .card:nth-child(2){border-bottom:1px solid var(--rule);}
  .science .head{grid-template-columns:1fr;gap:32px;}
  .paper{grid-template-columns:1fr;gap:6px;}
  .paper .stat{text-align:left;}
  .evidence-grid{grid-template-columns:1fr;gap:48px;}
  .reg-grid{grid-template-columns:1fr;gap:32px;}
  .reg-row{grid-template-columns:1fr;gap:6px;}
  .reg-row::before{display:none;}
  .bench{grid-template-columns:repeat(2,1fr);}
  .contact-grid{grid-template-columns:1fr;}
  .trust-inner{justify-content:flex-start;}
  .trust .marks{justify-content:flex-start;gap:20px;}
}